Dot Approved Anxiety Medications 2025. Dot disqualifying medications are substances that are deemed to potentially impair a driver’s ability to operate a commercial. If the anxiety disorder is controlled with the medication, then there is no real problem.

The dot list of disqualifying medications is designed to ensure that cdl drivers are not taking legal or illegal drugs that will interfere with their ability to operate a truck or cmv safely and legally. The following list of medications was compiled primarily to assist pilots however drivers and physicians may also.